Metabolic Potential versus Genome Size | Physics TomorrowABSTRACT In this work, we have shown that there is a connection between the metabolic potential (the coefficient ‘a’ in metabolic-mass relationship P=aMk, where P- basal metabolic rate, M- body mass, k - power coefficient) and the corresponding genome size (C-value diapason) of the given organismal taxon. With increase of the metabolic potential of living organisms in evolution, the C-value diapason of given taxon decreases. The study shows the metabolic and genomic characteristics of the simplest bacterial cells represent the natural scale. The metabolic and genomic characteristics of all more complex organisms that emerge after them are adjusted with this natural scale. This finding may provide an answer to genome-size enigma.